{"id":2005,"date":"2026-01-26T15:13:12","date_gmt":"2026-01-26T15:13:12","guid":{"rendered":"https:\/\/biotechcell.com.pe\/?page_id=2005"},"modified":"2026-02-02T15:42:08","modified_gmt":"2026-02-02T15:42:08","slug":"development-of-a-biochip","status":"publish","type":"page","link":"https:\/\/biotechcell.com.pe\/en\/development-of-a-biochip\/","title":{"rendered":"Advanced Molecular Bioelectronic Platform"},"content":{"rendered":"

A key challenge in microgravity was studying real-time gene expression. To overcome the limitations of bulky equipment like PCR, we developed a bioelectronic biochip integrating ultrasound lysis. This platform showed immediate translational potential for terrestrial diagnostics. By 2014, it had already been validated on multiple fronts: detection of HPV-16 via E6\/E7 proteins, the BCR-ABL1 marker for leukemia, SARS-CoV-2 with agreement to RT-PCR, and cardiovascular biomarkers using nanoparticles. Thus, this technology not only advances space research but also establishes a new generation of portable and automated diagnostics.<\/p>\n\n\n\n

BIOCHIP:<\/strong><\/p>\n\n\n\n

1. Human Papillomavirus (HPV)<\/a>:<\/strong><\/p>\n\n\n\n

Immobilization of molecular structures E6 and E7 on a carbon conductive substrate coated with a gold layer for the detection of HPV type 16 at the BIOTECHCELL SAC laboratory in 2024.<\/p>\n\n\n\n

2. Chronic Myeloid Leukemia (CML)<\/a>:<\/strong><\/p>\n\n\n\n

Immobilization of the BCR-ABL1 gene on a carbon conductive substrate coated with a gold layer for the detection of Chronic Myeloid Leukemia at the BIOTECHCELL SAC laboratory, 2024.<\/p>\n\n\n\n

3. Cardiovascular Diseases (DC)<\/a>:<\/strong><\/p>\n\n\n\n

Implementation of a diagnostic device through the immobilization of nanoparticles on a screen-printed gold electrode for the detection of cardiovascular diseases at the BIOTECHCELL SAC Laboratory in 2024<\/p>\n\n\n\n

4. Diagnostic Tests for COVID-19 (SARS-CoV-2):<\/strong><\/p>\n\n\n\n

Method validation for the detection of SARS-CoV-2 using Protobiochip, compared to the RT-PCR method, in samples from COVID-19 patients<\/a>.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

<\/p>\n\n\n\n

5. Diagnostic Tests for COVID-19 (SARS-CoV-2):<\/strong><\/p>\n\n\n\n

Method validation for the detection of neutralizing antibodies for SARS-CoV-2 using a Protobiochip, compared to the quantitative FIA test kit. Research project registered with the National Institute of Health (INS)<\/a>.<\/p>\n\n\n\n

\"\"\/<\/figure>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

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